Rotigotine

SL-11605

Rotigotine, >98%

CAS No. : [99755-59-6]

Synonyms : N-0923; (-)-N 0437

IUPAC Name : (S)-6-(Propyl(2-(thiophen-2-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Rotigotine is a potent dopamine receptor agonist, exhibiting Ki values of 0.71 nM for the dopamine D3 receptor, 4–15 nM for the D2, D5, and D4 receptors, and 83 nM for the dopamine D1 receptor. It also acts as a partial agonist at the 5-HT1A receptor and as an antagonist at the α2B-adrenergic receptor. Rotigotine can be utilized in Parkinson's disease (PD) research.

References : Wood M. et. al.: Br. J. Pharmacol.,172(4), 1124-35, 2015; Radad K. et. al.: Folia Neuropathol., 52(2), 179-86, 2014; Bertaina-Anglade V. et. al.: Eur. J. Pharmacol., 548(1-3), 106-14, 2006; Scheller D. et. al.: Naunyn Schmiedebergs Arch Pharmacol. 379(1), 73-86, 2009.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.