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Rotigotine hydrochloride

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SL-11606

Rotigotine hydrochloride, >98%

CAS No. : [125572-93-2]

Synonyms : N-0923 hydrochloride; (-)-N 0437 hydrochloride

IUPAC Name : (S)-6-(Propyl(2-(thiophen-2-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride

Price And Availability
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25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
50MGRequest A Quote
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250MGRequest A Quote
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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C19H25NOS • HCl
Mol. Weight :
351.93
Appearance :
Solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : Rotigotine hydrochloride is a potent dopamine receptor agonist, exhibiting Ki values of 0.71 nM for the dopamine D3 receptor, 4–15 nM for the D2, D5, and D4 receptors, and 83 nM for the dopamine D1 receptor. It also acts as a partial agonist at the 5-HT1A receptor and as an antagonist at the α2B-adrenergic receptor. Rotigotine hydrochloride can be utilized in Parkinson's disease (PD) research.

References : Wood M. et. al.: Br. J. Pharmacol.,172(4), 1124-35, 2015; Radad K. et. al.: Folia Neuropathol., 52(2), 179-86, 2014; Bertaina-Anglade V. et. al.: Eur. J. Pharmacol., 548(1-3), 106-14, 2006; Scheller D. et. al.: Naunyn Schmiedebergs Arch Pharmacol. 379(1), 73-86, 2009.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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