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Rotigotine O-thienyl ethyl hydrochloride

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Rotigotine O-thienyl ethyl hydrochloride, >98%

IUPAC Name : (S)-N-Propyl-5-(2-(thiophen-2-yl)ethoxy)-N-(2-(thiophen-2-yl)ethyl)-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride

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5MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C25H31NOS2 • HCl
Mol. Weight :
462.11
Appearance :
Beige solid (hygroscopic)
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Rotigotine, which is a potent dopamine receptor agonist. It also acts as a partial agonist at the 5-HT1A receptor and as an antagonist at the α2B-adrenergic receptor. Rotigotine can be utilized in Parkinson's disease (PD) research.

References : Wood M. et. al.: Br. J. Pharmacol.,172(4), 1124-35, 2015; Radad K. et. al.: Folia Neuropathol., 52(2), 179-86, 2014; Bertaina-Anglade V. et. al.: Eur. J. Pharmacol., 548(1-3), 106-14, 2006; Scheller D. et. al.: Naunyn Schmiedebergs Arch Pharmacol. 379(1), 73-86, 2009.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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