RS-127445 hydrochloride

SI-8148

RS-127445 hydrochloride, >98% (HPLC)

CAS No. : [199864-86-3]

IUPAC Name : 4-(4-Fluoronaphthalen-1-yl)-6-isopropylpyrimidin-2-amine hydrochloride

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : RS‑127445 hydrochloride blocks 5‑HT₂B receptors with high affinity (pK_i= 9.5) and shows ~1000‑fold selectivity over numerous other receptor and ion channel targets. Its potency and selectivity profile make it valuable for studying 5‑HT₂B‑dependent pathways in neurobiology and cardiovascular research.

References : Bonhaus D. W. et al.: Br. J. Pharmacol., 127(5), 1075-82, 1999; Bassil A. K. et al.: Br. J. Pharmacol., 158(1), 252-8, 2009.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.