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RS-25344 hydrochloride

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SI-5169

RS-25344 hydrochloride, >98% (HPLC)

CAS No. : [152815-28-6]

MDL No. : MFCD16618380

IUPAC Name : 1-(3-Nitrophenyl)-3-(pyridin-4-ylmethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione

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25MGRequest A Quote
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Chemical Properites
Mol. Formula :
C19H13N5O4 . HCl
Mol. Weight :
411.80
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : RS 25344 hydrochloride is a potent and selective phosphodiesterase (PDE) 4 inhibitor (IC50 values are 0.28, > 100, 160 and 330 nM at PDE4, PDE1, PDE2 and PDE3 respectively).

References : Kaneko T. et al. Cell Signal., 7(5), 527-34, 1995; Fisch D. J. et al.: Hum Reprod., 13(5), 1248-54, 1998; Will McDonough W. et al.: FASEB J. 34(9), 12533-12548,2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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