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Rufinamide

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SI-6583

Rufinamide, >98% (HPLC)

CAS No. : [106308-44-5]

Synonyms : CGP-33101; E-2080; RUF-331

IUPAC Name : 1-(2,6-Difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide

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Chemical Properites
Mol. Formula :
C10H8F2N4O
Mol. Weight :
238.2
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Rufinamide is an orally active antiepileptic drug that limits neuronal hyperexcitability through inhibition of Na⁺‑current activation, resulting in robust anticonvulsant activity. It serves as a key tool compound in mechanistic and therapeutic studies of Lennox–Gastaut syndrome.

References : Chen J. L. et al.: Neuropharmacology., 247, 109835, 2024; White H. S. et.al.: Epilepsia., 49(7), 1213-20, 2008; Suter M. R. et.al.: Anesthesiology., 118(1), 160-72, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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