Ruxolitinib

SI-1065

Ruxolitinib, >98% (HPLC)

CAS No. : [941678-49-5]

MDL No. : MFCD12031592

Synonyms : INCB018424

IUPAC Name : (R)-3-(4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	75.00		In Stock	Estimated to ship on 20 September 2026
10MG	125.00		In Stock	Estimated to ship on 20 September 2026
25MG	255.00		In Stock	Estimated to ship on 20 September 2026
50MG	455.00		In Stock	Estimated to ship on 20 September 2026
100MG	855.00		In Stock	Estimated to ship on 20 September 2026
250MG	1655.00		In Stock	Estimated to ship on 20 September 2026
500MG	2655.00		In Stock	Estimated to ship on 20 September 2026

Applications : Ruxolitinib is a potent and selective JAK1/2 inhibitor with IC50s of 3.3 nM and 2.8 nM in cell-free assays, and has 130-fold selectivity for JAK1/2 over JAK3.

References : Quintas-Cardama A. et al.: Blood 115(15), 3109-3117, 2010; Verstovsek S. et al.: N. Engl. J. Med., 366(9), 799-807, 2012; Harrison C. et al.: N. Engl. J. Med., 366(9), 787-798, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.