(S)-3-Hydroxy midostaurin

SL-5939

(S)-3-Hydroxy midostaurin, >98%

CAS No. : [945260-14-0]

Synonyms : (S)-CGP 52421

IUPAC Name : N-((5R,7R,8R,9S,14S)-14-Hydroxy-8-methoxy-9-methyl-16-oxo-6,7,8,9,15,16-hexahydro-5H,14H-17-oxa-4b,9a,15-triaza-5,9-methanodibenzo[b,h]cyclonona[jkl]cyclopenta[e]-as-indacen-7-yl)-N-methylbenzamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : (S)-3-Hydroxy midostaurin is a minor metabolite of Midostaurin, undergoing by the hepatic CYP3A4 enzyme. (S)-3-Hydroxy midostaurin has the potential for acute myeloid leukemia (AML). Midostaurin is a potent kinases inhibitor.

References : Fabbro D. et al.: Pharmacol Ther., 82(2-3), 293-301, 1999; Ikegami Y. et al.: Jpn. J. Pharmacol., 70(1), 65-72, 1996; Manley P. W. et al.: Biochemistry 57(38), 5576-5590, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.