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(S)-BAY 41-4109 enantiomer

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SI-7399

(S)-BAY 41-4109 enantiomer, >98% (HPLC)

CAS No. : [476617-51-3]

Synonyms : BAY 41-4109 (S)-enantiomer

IUPAC Name : Methyl (S)-6-(2-Chloro-4-fluorophenyl)-2-(3,5-difluoropyridin-2-yl)-4-methyl-1,6-dihydropyrimidine-5-carboxylate

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Chemical Properites
Mol. Formula :
C18H13ClF3N3O2
Mol. Weight :
395.77
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This less‑active enantiomer of BAY 41‑4109 shows markedly lower potency than the parent compound, a low‑nanomolar HBV inhibitor (IC50 = 53 nM) that targets HBV core‑protein assembly. It is applied in studies examining stereochemical contributions to antiviral activity.

References : Weber O. et al.: Antiviral. Res., 54(2), 69-78, 2002; Stray S. J. et al.: J. Mol. Recognit., 19(6), 542-8, 2006; Wu G. Y. et al.: J. Chemother., 20(4), 458-67, 2008.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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