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(S)-Crizotinib

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SL-1361

(S)-Crizotinib, >98%

CAS No. : [1374356-45-2]

MDL No. : MFCD22126092

IUPAC Name : 3-[(1S)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-pyridinamine

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Chemical Properites
Mol. Formula :
C21H22Cl2FN5O
Mol. Weight :
450.34
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : (S)-Crizotinib is the (S)-enantiomer of Crizotinib, which is a potent inhibitor of c-Met and ALK. Crizotinib is an anti-cancer drug, used for the treatment of non-small cell lung carcinoma (NSCLC). (S)-Crizotinib can also serve as a promising anticancer agent.

References : Huber K. V. M. et al.: Nature, 508, 222, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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