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(S,E)-4-(1-(4-(Prop-1-en-1-yl)-1-(4-(trifluoromethyl)benzyl)-1H-1,2,3-triazole-5-carboxamido)ethyl)benzoic acid

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SI-5627

(S,E)-4-(1-(4-(Prop-1-en-1-yl)-1-(4-(trifluoromethyl)benzyl)-1H-1,2,3-triazole-5-carboxamido)ethyl)benzoic acid, >98% (HPLC)

CAS No. : [2287259-07-6]

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5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Back Order  Estimated to ship on 04 October 2026
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Note: SI-5627 is not in stock but can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and Mass analysis. Purity (HPLC) is usually >98%. COA, QC data and SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or Request A Quote. We respond promptly. Thank You!
Chemical Properites
Mol. Formula :
C23H21F3N4O3
Mol. Weight :
458.44
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a highly potent and selective competitive prostanoid EP4 receptor antagonist for cancer immunotherapy.This inhibits human and mouse EP4 receptor with IC50s of 6.1 nM and 16.2 nM, respectively. IC50s >10 μM for human EP1, EP2,and EP3 receptors.

References : Yang J. J. et al.: J. Med. Chem., 63(2), 569-590, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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