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(S)-GLPG-0974

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SI-7913

(S)-GLPG-0974, >98% (HPLC)

CAS No. : [2326220-69-1]

IUPAC Name : (S)-4-(1-(Benzo[b]thiophene-3-carbonyl)-N-(3-chlorobenzyl)-2-methylazetidine-2-carboxamido)butanoic acid

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Chemical Properites
Mol. Formula :
C25H25ClN2O4S
Mol. Weight :
484.99
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : (S)-GLPG-0974 represents the stereochemical counterpart of GLPG0974 and is commonly used as a negative or inactive control in FFA2/GPR43 assays. GLPG-0974 itself is a highly potent FFA2 antagonist (IC50 = 9 nM).

References : Pizzonero M. et al.: J. Med. Chem., 57(23), 10044-57, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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