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(S)-Navlimetostat

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SI-6924

(S)-Navlimetostat, >98% (HPLC)

CAS No. : [2630904-44-6]

Synonyms : (S)-BMS-986504; (S)-MRTX-1719

IUPAC Name : 2-(4-(4-(Aminomethyl)-1-oxo-1,2-dihydrophthalazin-6-yl)-1-methyl-1H-pyrazol-5-yl)-4-chloro-6-cyclopropoxy-3-fluorobenzonitrile

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Chemical Properites
Mol. Formula :
C23H18ClFN6O2
Mol. Weight :
464.89
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : (S)-Navlimetostat is the (S)‑configured enantiomer of Navlimetostat and acts as a PRMT5–MTA complex inhibitor with relatively weak potency (IC50 = 7070 nM). Its profile makes it useful as a control compound for probing stereoselective PRMT5 inhibition.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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