(S)-Nor verapamil

SL-2319

(S)-Nor verapamil, >94% (HPLC)

CAS No. : [123931-31-7]

Related CAS No. : [147158-72-3] of the HCl compound

IUPAC Name : (S)-5-((3,4-Dimethoxyphenethyl)amino)-2-(3,4-dimethoxyphenyl)-2-isopropylpentanenitrile

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Applications : This is a metabolite of (S)-Verapamil. Both of its isomers inhibit the p-glycoprotein efflux pump in multidrug resistant tumor cells.

References : Peroutka S. et al.: J. Ann. Neurol, 23, 500, 1988; Eliason J. F. et al.: Int. J. Cancer, 46, 113, 1990.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.