(S)-Ruvonoflast

SI-7410

(S)-Ruvonoflast, >98% (HPLC)

Synonyms : (S)-NT-0796

IUPAC Name : Isopropyl (S)-2-(((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)oxy)-3-(pyrimidin-2-yl)propanoate

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : (S)-Ruvonoflast is the (S)‑configured form of Ruvonoflast, a selective and orally active NLRP3 inflammasome inhibitor capable of CNS penetration. It supports research on NLRP3‑mediated inflammatory and neurodegenerative conditions.

References : David H. et al.: J. Med. Chem., 66(21), 14897-14911, 2023; Thornton P. et al.: J. Pharmacol. Exp. Ther., 388(3), 813-826, 2024; Smolak P. et al.: J. Pharmacol. Exp.Ther., 388(3), 798-812, 2024; Doedens J. R. et al.: Biochem. Pharmacol., 227, 116455, 2024.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.