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(S,S)-Hydroxy bupropion

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(S,S)-Hydroxy bupropion, >98%

CAS No. : [192374-14-4]

IUPAC Name : (2S,3S)-2-(3-Chlorophenyl)-3,5,5-trimethylmorpholin-2-ol

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Chemical Properites
Mol. Formula :
C13H18ClNO2
Mol. Weight :
255.74
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
Acetonitrile
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an active metabolite of Bupropion, which is a norepinephrine/dopamine-reuptake inhibitor (NDRI). Bupropion is used most commonly for the management of major depressive disorder (MDD), seasonal affective disorder (SAD), and as an aid for smoking cessation.

References : Moreira R. Clin Drug Investig., 31 Suppl 1: 5-17, 2011; Foley K. F. et al.: Expert Rev Neurother., 6(9), 1249-1265, 2006; Stahl S. M. et al.: Prim Care Companion J. Clin. Psychiatry 6(4),159-166, 2004.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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