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(S)-Suvorexant

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(S)-Suvorexant, >98%

CAS No. : [1030377-80-0]

Synonyms : Suvorexant enantiomer

IUPAC Name : (S)-(4-(5-Chlorobenzo[d]oxazol-2-yl)-7-methyl-1,4-diazepan-1-yl)(5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone

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Chemical Properites
Mol. Formula :
C23H23ClN6O2
Mol. Weight :
450.93
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an opposite enantiomer of Suvorexant, which is a potent, CNS penetrant, orally available, dual orexin receptor antagonist. It is used to treat insomnia.

References : Flick C. A. et al.: Bioorg. Med. Chem. 24(9), 1937-1980, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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