S1P1 agonist

SI-6407

S1P1 agonist, >98% (HPLC)

IUPAC Name : ((1R,3S)-1-Amino-3-((S)-6-(3-ethoxypropyl)-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopentyl)methanol

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : This is a highly potent, biased S1P1 agonist derived from the BMS‑986104 series. Structural optimization of the alkyl side chain (olefin/ether/thioether/glycol variants) gives this compound a shorter in vivo half‑life, enhanced formation of the active phosphate metabolite, and robust efficacy in arthritis models, while maintaining the improved cardiovascular and pulmonary safety profile characteristic of biased S1P1 modulators.

References : Gilmore L. J. et al.: J. Med. Chem., 64(3), 1454-1480, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.