Sacubitril

SL-2389

Sacubitril, >98%

CAS No. : [149709-62-6]

MDL No. : MFCD00920862

Synonyms : AHU-377

IUPAC Name : 4-(((2S,4R)-1-([1,1'-Biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoic acid

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
1G	135.00		In Stock	Estimated to ship on 20 September 2026
5G	465.00		In Stock	Estimated to ship on 20 September 2026

Applications : Sacubitril is a potent NEP inhibitor with an IC₅₀ of 5 nM. Sacubitril is a component of the heart failure medicine of LCZ696.

References : Ksander G. M. et al.: J. Med. Chem., 38(10), 1689-700,1995; Voors A. A. et al.: Expert Opin Investig Drugs 22(8), 1041-1047, 2013; von Lueder T. G. et al. Circ Heart Fail. 8(1), 71-78, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.