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Sacubitril impurity 22

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SL-3977

Sacubitril impurity 22, >98%

CAS No. : [1012341-48-8]

MDL No. : MFCD28386950

IUPAC Name : (S,E)-5-([1,1'-Biphenyl]-4-yl)-4-amino-2-methylpent-2-enoic acid

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
1G10.00
Back Order  Estimated to ship on 20 September 2026
5G20.00
Back Order  Estimated to ship on 20 September 2026
25G60.00
Back Order  Estimated to ship on 20 September 2026
100G155.00
Back Order  Estimated to ship on 20 September 2026
500G595.00
Back Order  Estimated to ship on 20 September 2026
We accept
Chemical Properites
Mol. Formula :
C23H27NO4
Mol. Weight :
381.46
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Sacubitril (Sacubitril impurity 22), which is a potent NEP inhibitor. Sacubitril is a component of the heart failure medicine LCZ696 (Sacubitril / Valsartan).

References : Ksander G. M. et al.: J. Med. Chem., 38(10), 1689-700,1995; Voors A. A. et al.: Expert Opin Investig Drugs 22(8), 1041-1047,2013; von Lueder T. G. et al.: Circ Heart Fail. 8(1), 71-78, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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