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Sacubitril impurity 7

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SL-3962

Sacubitril impurity 7, >98%

CAS No. : [1012341-52-4]

IUPAC Name : (2S,4S)-5-([1,1'-Biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid

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Chemical Properites
Mol. Formula :
C23H29NO4
Mol. Weight :
383.48
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Sacubitril (Sacubitril impurity 7), which is a potent NEP inhibitor. Sacubitril is a component of the heart failure medicine LCZ696 (Sacubitril / Vlsartan).

References : Ksander G. M. et al.: J. Med. Chem., 38(10), 1689-700,1995; Voors A. A. et al.: Expert Opin Investig Drugs 22(8), 1041-1047,2013; von Lueder T. G. et al.: Circ Heart Fail. 8(1), 71-78, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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