SAE-14

SI-7430

SAE-14, >98% (HPLC)

CAS No. : [1241280-25-0]

Synonyms : GPR183 antagonist-1

IUPAC Name : 3-(3,4-Difluorophenyl)-N-(3-fluoro-5-morpholinophenyl)propanamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : SAE‑14 selectively antagonizes GPR183 with low‑nanomolar potency (IC₅₀ = 28.5 nM) and suppresses 7α,25‑OHC–driven calcium signaling in HL‑60 cells with IC₅₀ values below 50 nM. It also reverses allodynia in mice, making it valuable for studying GPR183‑dependent immune regulation and pain modulation.

References : Braden K. et al.: J. Pharmacol. Exp. Ther., 375(2), 367-375, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.