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Samotolisib

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SI-5332

Samotolisib, >98% (HPLC)

CAS No. : [1386874-06-1]

MDL No. : MFCD28411368

Synonyms : LY3023414

IUPAC Name : (S)-8-(5-(2-Hydroxypropan-2-yl)pyridin-3-yl)-1-(2-methoxypropyl)-3-methyl-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one

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Chemical Properites
Mol. Formula :
C23H26N4O3
Mol. Weight :
406.49
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Samotolisib is a dual inhibitor of phosphoinositide 3-kinase (PI3K) mammalian target of rapamycin (mTOR). Samotolisib has been used in trials studying the treatment of neoplasm, solid tumor, colon cancer, brest cancer and advanced cancer, among others.

References : Smith C. M. et al.: Cancer Ther., 15(10), 2344-2356, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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