SAR-407899

SI-6306

SAR-407899, >98% (HPLC)

CAS No. : [923359-38-0]

IUPAC Name : 6-(Piperidin-4-yloxy)isoquinolin-1(2H)-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : SAR-407899 selectively inhibits ROCK2 with sub‑hundred‑nanomolar affinity (IC₅₀ = 135 nM; K_i = 36–41 nM) and demonstrates stable inhibition of migrasome formation, making it a valuable tool for probing ROCK‑dependent cytoskeletal and membrane‑dynamics pathways.

References : Löhn M. et al.: Hypertension., 54(3), 676-83, 2009; Guagnini F. et al.: J. Transl. Med., 10, 59, 2012; Lu P. et al.: Cell Discov., 6(1), 51, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.