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SB-1578

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SI-6334

SB-1578, >98% (HPLC)

CAS No. : [937273-04-6]

Synonyms : CT-1578

IUPAC Name : (E)-44-(2-(Pyrrolidin-1-yl)ethoxy)-6,11-dioxa-3-aza-2(4,2)-pyrimidina-1(2,5)-furana-4(1,3)-benzenacyclododecaphan-8-ene

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25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C26H30N4O4
Mol. Weight :
462.55
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : SB-1578 is a potent and selective inhibitor of JAK2 and FLT3, demonstrating low‑nanomolar activity and minimal off‑target kinase engagement. It is useful for probing JAK2‑dependent inflammatory pathways and for research in rheumatoid arthritis and related immune‑mediated conditions.

References : Poulsen A. et al.: J. Comput. Aided. Mol. Des., 26(4), 437-50, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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