SB-202190

SI-7744

SB-202190, >98% (HPLC)

CAS No. : [152121-30-7]

IUPAC Name : 4-(4-(4-Fluorophenyl)-5-(pyridin-4-yl)-1H-imidazol-2-yl)phenol

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : SB-202190 selectively inhibits p38 MAPK (IC₅₀ = 50 nM for p38α; 100 nM for p38β₂) and binds the ATP‑binding site of recombinant human p38 (K_d = 38 nM). It shows anticancer activity, improves memory deficits in vivo, and promotes autophagy, making it a versatile tool compound for studying stress‑response signaling.

References : Davies S. P. et al.: Biochem J. 351(Pt 1), 95-105, 2000; Nemoto S. et al.: J. Biol. Chem., 273(26), 16415-20, 1998; Manthey C. L. et al.: J. Leukoc Biol., 64(3), 409-17, 1998.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.