SB-202190 hydrochloride

SI-7745

SB-202190 hydrochloride, >98% (HPLC)

CAS No. : [350228-36-3]

IUPAC Name : 4-(4-(4-Fluorophenyl)-5-(pyridin-4-yl)-1H-imidazol-2-yl)phenol hydrochloride

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : SB-202190 hydrochloride selectively inhibits p38 MAPK (IC₅₀ = 50 nM for p38α; 100 nM for p38β₂) and binds the ATP pocket of recombinant human p38 (K_d = 38 nM). It shows notable anticancer effects and promotes autophagy, supporting its use in studies of MAPK‑regulated stress signaling and tumor biology.

References : Davies S. P. et al.: Biochem. J., 351(Pt 1), 95-105, 2000; Yang S. et al.: Biomed. Res. Int., 215798, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.