SB-225002

SI-7314

SB-225002, >98% (HPLC)

CAS No. : [182498-32-4]

IUPAC Name : 1-(2-Bromophenyl)-3-(2-hydroxy-4-nitrophenyl)urea

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : SB-225002 functions as a potent and selective CXCR2 antagonist, inhibiting ¹²⁵I‑IL‑8 binding with an IC₅₀ of 22 nM. Its pharmacological profile supports its use in dissecting CXCR2‑dependent inflammatory pathways.

References : White J. R. et al.: J. Biol. Chem., 273(17), 10095-8, 1998; Wang B. et al.: Cancer Res, 66(6), 3071-7, 2006; Herz J. et al.: Stroke, 46(10), 2916-25, 2015; Wang L. Y. et al.: J. Neuroinflammation, 13(6), 2016; Shi Z. R. et al.: J. Autoimmun., 30-40, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.