SB-415286

SI-7864

SB-415286, >98% (HPLC)

CAS No. : [264218-23-7]

IUPAC Name : 3-((3-Chloro-4-hydroxyphenyl)amino)-4-(2-nitrophenyl)-1H-pyrrole-2,5-dione

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : SB‑415286 is a selective GSK‑3 inhibitor that potently targets GSK‑3α (IC₅₀ = 77.5 nM; Kᵢ = 30.75 nM) and displays comparable activity toward GSK‑3β. Its cell‑permeable profile supports its use in studies of GSK‑3–dependent cellular processes.

References : Coghlan M. P. et al.: Chem. Biol., 7(10), 793-803, 2000; Cross D. A. et al.: J. Neurochem., 77(1), 94-102, 2001; Mazor M. et al.: Oncogene., 23(47), 7882-92, 2004.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.