SB-649868

SI-4660

SB-649868, >98% (HPLC)

CAS No. : [380899-24-1]

MDL No. : MFCD18251524

Synonyms : GSK-649868

IUPAC Name : (S)-N-((1-(5-(4-Fluorophenyl)-2-methylthiazole-4-carbonyl)piperidin-2-yl)methyl)benzofuran-4-carboxamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : SB-649868 is a potent and selective orally active orexin (OX) 1 and OX2 receptor antagonist (pKi =9.4 and 9.5 at the OX1 and OX2 receptor, respectively).

References : Renzulli C. et al.: Drug Metab Dispos. 39(2), 215-227, 2011; Bettica P. et al.: Neuropsychopharmacology 37(5), 1224-1233,2012; Piccoli L. et al.: Neuropsychopharmacology 37(9),1999-2011, 2012; Di Fabio R. et al.: Bioorg Med Chem Lett., 21(18), 5562-5567, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.