SB-674042

SI-5710

SB-674042, >98% (HPLC)

CAS No. : [483313-22-0]

MDL No. : MFCD18251550

IUPAC Name : (S)-(5-(2-Fluorophenyl)-2-methylthiazol-4-yl)(2-((5-phenyl-1,3,4-oxadiazol-2-yl)methyl)pyrrolidin-1-yl)methanone

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
Note: SB-674042 is not in stock but can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and Mass analysis. Purity (HPLC) is usually >98%. COA, QC data and SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or Request A Quote. We respond promptly. Thank You!

Applications : SB-674042 is a potent and selective non-peptide orexin 1 (OX1) receptor antagonist (Kd = 3.76 nM); exhibits 100-fold selectivity for OX1 over OX2 receptors.

References : Alexander A. et al.: Biochemistry 51(15), 3178-3197, 2012; Malherbe P. et al.: Molecular Pharmacology 78(1), 81-93, 2010; Malherbe P. et al.: Molecular Pharmacology 76(3), 618-631, 2009; Ellis J. et al.: Journal of Biological Chemistry 281(50), 38812-38824, 2006; Langmead J. C. et al.: B. J. Pharmacol., 141(2), 340-346, 2004.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.