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SC-60

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SI-6256

SC-60, >98% (HPLC)

CAS No. : [1207455-75-3]

IUPAC Name : 1,3-Bis(3-(4-cyanophenoxy)-4-methylphenyl)urea

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Chemical Properites
Mol. Formula :
C29H22N4O3
Mol. Weight :
474.52
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : SC‑60 is a Sorafenib analog, activates SHP‑1 to block STAT3 signaling and suppress downstream survival proteins such as Bcl‑2, Cyclin D1, and Survivin. It shows potent antiproliferative activity in HCC cell lines and induces caspase‑mediated apoptosis. In vivo, SC‑60 significantly inhibits tumor progression in xenograft models, highlighting its relevance for HCC studies.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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