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SCO-120

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SI-8094

SCO-120, >98% (HPLC)

IUPAC Name : (S,E)-3-(3,5-Difluorophenyl)-2-(4-(3-(3-(fluoromethyl)azetidin-1-yl)prop-1-en-1-yl)phenyl)-4-methyl-2H-chromen-7-ol

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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C29H26F3NO2
Mol. Weight :
477.53
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : SCO‑120 is an orally bioavailable selective estrogen receptor degrader (SERD) with potential antineoplastic activity. It binds to wild‑type and mutant ERα, including clinically relevant ESR1 mutations Y537S and D538G, inducing conformational changes that lead to ER degradation and suppression of ER‑mediated signaling.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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