Scopolamine-d3 hydrobromide

SL-8914

Scopolamine-d₃ hydrobromide, >98%

CAS No. : [1279037-70-5]

Synonyms : (-)-Scopolamine-d₃ hydrobromide; Hyoscine-d₃ hydrobromide

IUPAC Name : (1R,2R,4S,5S,7s)-9-(Methyl-d₃)-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-yl (S)-3-hydroxy-2-phenylpropanoate hydrobromide

Price And Availability
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5MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
10MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
25MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
50MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026

Applications : This is a deuterium labelled version of Scopolamine hydrobromide, which is a high-affinity muscarinic antagonist that can cross the blood-brain barrier. It competitively antagonizes 5-HT3 receptors with an IC50 of 2.09 μM. This can induce cognitive and memory deficits in animals. It can be used in the research of preventing postoperative nausea and vomiting, motion sickness, nervous system diseases.

References : Lochner M. et al.: Neuropharmacology 108, 220-228, 2016; Pattanashetti L. A. et al.: Indian J Pharmacol., 49(1), 60-64, 2017; Yadang F. S. A. et al.: Int. J. Alzheimers Dis., 6372059, 2020; Klinkenberg I. et al.: Neurosci Biobehav Rev., 34(8), 1307-1350, 2010; Nicha Puangmalai N. et al.: Neural Regen Res., 12(9), 1492-1498, 2017; Budzynska B. et al.: Psychopharmacology (Berl). 232(5), 931-942, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.