SCR-2682

SI-7662

SCR-2682, >98% (HPLC)

CAS No. : [1584711-40-9]

IUPAC Name : N-(4-(2-Bromo-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)-2,6-dimethylphenyl)-3,3-dimethylbutanamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : SCR-2682 robustly activates Kv7.2/7.3 channels with nanomolar potency (EC₅₀ = 9.8 nM), far surpassing retigabine in efficacy (~100‑fold). By enhancing M‑current, SCR2682 serves as a powerful probe for studying Kv7‑dependent regulation of membrane excitability and neuronal stabilization.

References : Chen X. T. et al.: J. Med. Chem., 56(20), 8019-31, 2013; DeWire S. M. et al.: J. Pharmacol Exp Ther., 344(3), 708-17, 2013; Schneider S. et al.: Biochemistry, 55(46), 6456-6466, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.