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CAS No. : [1423715-37-0]
Synonyms : SP-2577
IUPAC Name : (E)-N'-(1-(5-Chloro-2-hydroxyphenyl)ethylidene)-3-((4-methylpiperazin-1-yl)sulfonyl)benzohydrazide
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 250MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 500MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C20H23ClN4O4S | Mol. Weight : 450.94 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : Seclidemstat is a reversible, noncompetitive LSD1/KDM1A inhibitor with nanomolar potency (Ki = 31 nM; IC50 = 13 nM). It enhances antitumor immune responses in SWI/SNF‑mutant ovarian cancer and exhibits antiviral effects by blocking viral replication and late gene expression. Seclidemstat is also a key tool compound for Ewing sarcoma research.
References : Dai X. J. et al.: J. Med. Chem., 64(5), 2466-2488, 2021; Soldi R. et al.: PLoS One, 15(7), e0235705, 2020.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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