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Selexipag acid 1-N-oxide

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SL-2408

Selexipag acid 1-N-oxide, >98%

Synonyms : MRE-269 1-N-Oxide

IUPAC Name : N-(4-(Crboxymethoxy)butyl)-N-isopropyl-5,6-diphenylpyrazin-2-amine oxide

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Chemical Properites
Mol. Formula :
C25H29N3O4
Mol. Weight :
435.52
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Selexipag acid 1-N-oxide is metabolite of Selexipag. The drug is first hydrolyzed to an active metabolite, ACT 333679 (CAS No: 475085-57-5, planned) in the liver and then oxidized afterwards.

References : Orie N. N. et al.: Prostaglandins Other Lipid Mediat.,106, 1-7, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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