Selexipag impurity D

SL-4055

Selexipag impurity D, >98%

CAS No. : [475084-96-9]

Synonyms : Selexipag acid tert-butyl ester

IUPAC Name : tert-Butyl 2-(4-((5,6-diphenylpyrazin-2-yl)(isopropyl)amino)butoxy)acetate

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Applications : This is an advanced key intermediate in the preparation of Selexipag and related analogs. Selexipag is a nonprostanoid prostaglandin I2 (PGI-2) receptor agonist. Also this is an impurity of Selexipag (Selexipag impurity D).

References : Kuwano K. et al.: J. Pharmacol Exp Ther., 322(3), 1181-1188, 2007; Mous D. S. et al.: Am. J. Physiol Lung Cell Mol Physiol., May 10, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.