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CAS No. : [1393477-72-9]
Synonyms : KPT-330
IUPAC Name : (Z)-3-(3-(3,5-Bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-N'-(pyrazin-2-yl)acrylohydrazide
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 5MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 10MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C17H11F6N7O | Mol. Weight : 443.31 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : Selinexor is a KPT‑185 analog that selectively targets CRM1 with oral activity. Through inhibition of CRM1‑dependent nuclear export, it triggers PANoptosis and exerts potent antitumor effects, supporting its use in studies of nuclear‑export dysregulation and cancer therapy.
References : Etchin J. et al.: Br. J. Haematol., 161(1), 117-27, 2013; Tai Y. T. et al.: Leukemia, 28(1), 155-65, 2014; Camilli S. et al.: Cell Biochem. Biophys., 81(3), 421-426, 2023.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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