Selnoflast

SI-7359

Selnoflast, >98% (HPLC)

CAS No. : [2260969-36-4]

Synonyms : Somalix; RO-7486967; IZD-334; RG-6418

IUPAC Name : 1-Ethyl-N-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)piperidine-4-sulfonamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Selnoflast is a reversible, orally active NLRP3 inhibitor with high potency and selectivity. It effectively suppresses IL‑1β secretion in NLRP3‑activated AD patient–derived macrophages and shows promise for investigating NLRP3‑driven pathology in Alzheimer’s disease, ulcerative colitis, and chronic obstructive pulmonary disease.

References : Klughammer B. et al.: Clin Transl Med, 13(11), e1471, 2023; Vande Walle L. et al.: Nat. Rev. Drug Discov., 2023; Silvis M. J. M. et al.: Biomedicines, 10(12), 3056, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.