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Selnoflast calcium

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SI-7362

Selnoflast calcium, >98% (HPLC)

CAS No. : [2887416-19-3]

Synonyms : Somalix calcium; RO-7486967 calcium; IZD-334 calcium; RG-6418 calcium

IUPAC Name : 1-Ethyl-N-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)piperidine-4-sulfonamide, calcium salt

Price And Availability
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25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
50MGRequest A Quote
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100MGRequest A Quote
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250MGRequest A Quote
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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C20H29N3O3S • Ca
Mol. Weight :
391.53
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Selnoflast calcium is a reversible, orally active NLRP3 inhibitor with high potency and selectivity. It effectively suppresses IL‑1β secretion in NLRP3‑activated AD patient–derived macrophages and shows strong potential for investigating NLRP3‑driven pathology in Alzheimer’s disease, ulcerative colitis, and chronic obstructive pulmonary disease.

References : Vande Walle L. et al.: Nat. Rev. Drug. Discov., 2023 ; Klughammer B. et al.: Clin. Transl. Med., 13(11), e1471, 2023; Silvis. M. J. M. et al.: Biomedicines, 10(12), 3056, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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