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Selnoflast monopotassium

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SI-7361

Selnoflast monopotassium, >98% (HPLC)

Synonyms : Somalix monopotassium; RO-7486967 monopotassium; IZD-334 monopotassium; RG-6418 monopotassium

IUPAC Name : Potassium ((1-ethylpiperidin-4-yl)sulfonyl)((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)amide

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
50MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
100MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
250MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
500MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
We accept
Chemical Properites
Mol. Formula :
C20H28N3O3S- • K+
Mol. Weight :
429.62
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Selnoflast is a reversible, orally active NLRP3 inhibitor with high potency and selectivity. It effectively suppresses IL‑1β secretion in NLRP3‑activated AD patient–derived macrophages and shows strong potential for investigating NLRP3‑driven pathology in Alzheimer’s disease, ulcerative colitis, and chronic obstructive pulmonary disease.

References : Klughammer B. et al.: Clin. Transl.Med., 13(11), e1471, 2023; Vande Walle L. et al.: Nat. Rev. Drug Discov., 2023; Silvis. M. J. M. et al.: Biomedicines, 10(12), 3056, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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