Selonsertib hydrochloride

SI-6108

Selonsertib hydrochloride, >98% (HPLC)

CAS No. : [1448428-05-4]

Synonyms : GS-4997 hydrochloride

IUPAC Name : 5-(4-Cyclopropyl-1H-imidazol-1-yl)-2-fluoro-N-(6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)-4-methylbenzamide hydrochloride

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Selonsertib hydrochloride is an orally bioavailable ASK1 inhibitor that blocks kinase activation by targeting the catalytic domain. It suppresses cytokine production, downregulates fibrosis‑associated genes, and mitigates excessive apoptosis and aberrant cell growth, supporting its use in inflammation, fibrosis, and tumor‑biology research.

References : Lanier M. et al.: ACS Med. Chem. Lett., 8(3), 316-320, 2017; Lin J. H. et al.: Nephron, 129(1), 29-33, 2015; Loomba R. et al.: Hepatology, 67(2), 549-559, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.