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Selpercatinib amide impurity

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Selpercatinib amide impurity, >98%

CAS No. : [2817648-27-2]

IUPAC Name : 6-(2-Hydroxy-2-methylpropoxy)-4-(6-(6-((6-methoxypyridin-3-yl)methyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)pyrazolo[1,5-a]pyridine-3-carboxamide

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Chemical Properites
Mol. Formula :
C29H33N7O4
Mol. Weight :
543.63
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Selpercatinib, which is a potent and specific RET (c-RET) inhibitor for the treatment of non-small cell lung cancer, medullary thyroid cancer, and other types of thyroid cancers.

References : Senturk R. et. al.: J. Chromatogr B Analyt. Technol Biomed Life Sci.,1147, 122131, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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