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CAS No. : [1449228-40-3]
Synonyms : SNX2-1-165; BCD-115
IUPAC Name : 4-((2-(6-(4-Methylpiperazine-1-carbonyl)naphthalen-2-yl)ethyl)amino)quinazoline-6-carbonitrile
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 5MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 10MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C27H26N6O | Mol. Weight : 450.55 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : Senexin-B potently inhibits CDK8 and CDK19 with Kd values of 140 nM and 80 nM, respectively, and displays excellent aqueous solubility and bioavailability. These characteristics make it a valuable tool compound for probing CDK8/19‑dependent transcriptional pathways.
References : McDermott M. S. et al.: Oncotarget., 8(8), 12558-12575, 2017.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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