SGI-1027

SI-6679

SGI-1027, >98% (HPLC)

CAS No. : [1020149-73-8]

IUPAC Name : N-(4-((2-Amino-6-methylpyrimidin-4-yl)amino)phenyl)-4-(quinolin-4-ylamino)benzamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : SGI‑1027 inhibits DNMT3B, DNMT3A, and DNMT1 with IC₅₀ values of 7.5–12.5 µM in poly(dI‑dC)‑based assays. It serves as a useful tool compound for probing DNMT‑dependent epigenetic mechanisms.

References : Datta J. et al.: Cancer Res., 69(10), 4277-85, 2009; Rilova E. et al.: Chem. Med. Chem., 9(3), 590-601, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.