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SGI-110

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SL-1481

SGI-110, >96%

CAS No. : [929901-49-5]

MDL No. : MFCD28144509

Related CAS No. : [929904-85-8] of the sodium salt compound

Synonyms : 2’-Deoxy-5-azacytidylyl-(3’→5’)-2’-deoxy-guanosine; Guadecitabine

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Chemical Properites
Mol. Formula :
C18H24N9O10P
Mol. Weight :
557.41
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : SGI-110 is a DNA methyltransferases (DNMT) inhibitor in vivo and was shown to effectively tolerated in tumor-free mouse and was found to be similarly effective in reducing tumor growth.

References : Foulks J. M. et al.: J. Biomol Screen., Jan 17(1), 2-17, 2012; Coral S. et al.: Cancer Immunol Immunother., Mar 62(3), 605-14, 2013; Chuang J. C. et al.: Mol. Cancer. Ther., May 9(5),1443-50, 2010.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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