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SGI-110 (sodium salt)

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SL-1482

SGI-110 (sodium salt), >96%

CAS No. : [929904-85-8]

MDL No. : MFCD28138338

Related CAS No. : [929901-49-5] of the free acid compound

Synonyms : Guadecitabine sodium salt

IUPAC Name : 2’-Deoxy-5-azacytidylyl-(3’→5’)-2’-deoxy-guanosine sodium salt

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Chemical Properites
Mol. Formula :
C18H23N9NaO10P
Mol. Weight :
579.39
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : SGI-110 (sodium salt) is a DNA methyltransferases (DNMT) inhibitor in vivo and was shown to effectively tolerated in timor-free mouse and was found to be similarly effective in reducing tutor growth.

References : Foulks J. M. et al.: J. Biomol Screen., Jan 17(1), 2-17, 2012; Coral S. et al.: Cancer Immunol Immunother., Mar 62(3), 605-14, 2013; Chuang J. C. et al.: Mol. Cancer. Ther., May 9(5),1443-50,2010.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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