SGX-523

SI-8044

SGX-523, >98% (HPLC)

CAS No. : [1022150-57-7]

IUPAC Name : 6-((6-(1-Methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)thio)quinoline

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : SGX-523 is a highly potent and exceptionally selective ATP‑competitive MET inhibitor (IC₅₀ = 4 nM) that maintains >1,000‑fold selectivity over other kinases. It efficiently blocks MET‑dependent signaling pathways and demonstrates strong antitumor effects.

References : Buchanan S. G. et al.: Mol. Cancer Ther., 8(12), 3181-3190, 2009.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.