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CAS No. : [1309357-15-0]
Synonyms : CX-4945 sodium salt
IUPAC Name : Sodium 5-((3-chlorophenyl)amino)benzo[c][2,6]naphthyridine-8-carboxylate
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 250MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 500MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C19H11ClN3NaO2 | Mol. Weight : 371.76 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : Silmitasertib sodium salt is a potent, orally bioavailable CK2 inhibitor with low‑nanomolar activity (IC50 = 1 nM for CK2α/α′). It effectively blocks CK2‑dependent signaling processes implicated in tumor growth and cellular proliferation.
References : Siddiqui-Jain A. et al.: Cancer Res., 70(24), 10288-98, 2010; Buontempo F. et al.: Oncotarget., 7(2), 1323-40, 2016; Chon H. J. et al.: Front Pharmacol., 6, 70, 2015.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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